The project was geared to identifying agents both synthetic and natural that were effective during interrogation. The project was centered around, but not restricted to, the use of Anabasis aphylla (an alkaloid), scopolamine and mescaline.
Project Chatter was halted in 1953, presumably due to limited progress and the success of other projects.
- Goliszek, Andrew (2003). In the Name of Science: A History of Secret Programs, Medical Research, St. Martins Press. ISBN 978-0312303563.